What personal impact might substance abuse have on an individual?

Substance abuse can significantly disrupt an individual's life, leading to an inability to perform daily activities. This impairment can manifest in various ways, such as difficulties with physical tasks, neglect of personal hygiene, struggles with maintaining employment, and challenges in managing responsibilities at home or in social settings. The cognitive and physical impairments caused by substance abuse can hinder a person's ability to concentrate, follow through on commitments, and engage in necessary routines, ultimately affecting their overall quality of life. In contrast, the other options indicate positive outcomes that are generally not associated with substance abuse, making them less reflective of the realities faced by individuals struggling with this issue.